SNAPIN anticorps (AA 51-136)

N° du produit ABIN1386536

L’anticorps Lapin Polyclonal anti-SNAPIN a été validé pour ICC, ELISA, IF (cc), IF (p), IHC (p) et IHC (fro). Il convient pour détecter SNAPIN dans des échantillons de Humain.

Aperçu rapide pour SNAPIN anticorps (AA 51-136) (ABIN1386536)

Antigène: SNAPIN (SNAP-Associated Protein (SNAPIN))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNAPIN est non-conjugé

Application: Immunocytochemistry (ICC), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-SNAPIN anticorps

Épitope: AA 51-136

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SNAP25BP

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur SNAPIN

Antigène: SNAPIN (SNAP-Associated Protein (SNAPIN))

Autre désignation: SNAPIN/SNAP25BP

Sujet:

Synonyms: SNAP associated protein, SNAP-25-binding protein, SNAP-associated protein, SNAP25BP, SNAPAP, SNAPIN, SNAPN_HUMAN, SNARE associated protein snapin, SNARE-associated protein Snapin, Synaptosomal associated protein 25 binding protein, Synaptosomal-associated protein 25-binding protein, OTTHUMP00000035157.

Background: The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012].

ID gène: 23557

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis