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Serotonin Receptor 5A anticorps (AA 1-110)

Cet anticorps anti-Serotonin Receptor 5A est un anticorps Lapin Polyclonal détectant Serotonin Receptor 5A dans ELISA, IHC (p), ICC, IF (cc), IF (p) et IHC (fro). Adapté pour Rat. Ce Primary Antibody a été cité dans 1 publication.
N° du produit ABIN1386672

Aperçu rapide pour Serotonin Receptor 5A anticorps (AA 1-110) (ABIN1386672)

Antigène

Voir toutes Serotonin Receptor 5A (HTR5A) Anticorps
Serotonin Receptor 5A (HTR5A)

Reactivité

  • 32
  • 8
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Rat

Hôte

  • 34
  • 2
Lapin

Clonalité

  • 34
  • 2
Polyclonal

Conjugué

  • 29
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Serotonin Receptor 5A est non-conjugé

Application

  • 20
  • 17
  • 10
  • 8
  • 7
  • 3
  • 1
  • 1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Épitope

    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-110

     Réactivité croisée

    Rat

    Homologie

    Human,Mouse

    Purification

    Purified by Protein A.

    Immunogène

    KLH conjugated synthetic peptide derived from human 5HT5A receptor/SR-5A

    Isotype

    IgG
  • Indications d'application

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Date de péremption

    12 months
  • García-Pedraza, Hernández-Abreu, Morán, Carretero, García-Domingo, Villalón: "Role of peripheral 5-HT5A receptors in 5-HT-induced cardiac sympatho-inhibition in type 1 diabetic rats." dans: Scientific reports, Vol. 10, Issue 1, pp. 19358, (2021) (PubMed).

  • Antigène

    Serotonin Receptor 5A (HTR5A)

    Autre désignation

    5HT5A receptor/SR-5A

    Sujet

    Synonyms: HTR5A, 5 HT 5A, 5 hydroxytryptamine 5A receptor, 5-HT-5, 5-HT-5A, 5-HT5A, 5-hydroxytryptamine receptor 5A, 5HT5A, 5HT5A_HUMAN, HTR5A, Serotonin receptor 5A.

    Background: SR-5B, also designated 5-hydroxytryptamine (serotonin) receptor 5B (5-HT5B) and G protein-coupled receptor 134 (GPR134) is a receptor for the monoamine ligand serotonin (5-hydroxytryptamine, 5-HT). Serotonin is a neurotransmitter derived from serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract. Serotonin actions are mediated by receptors that influence the biochemistry of depression, anxiety, sexuality and appetite. Rat SR-5B is present in serotonergic neurons in dorsal raphe (DR) and central superior nucleus (CS, median raphe nucleus). DR cell bodies showing SR-5B mRNA expression are abundant in the medial portions of the nucleus. CS coexpression of SR-5B receptor mRNA with serotonin transporter mRNA is high in the intermediate portions of the nucleus. Serotonin receptors include SR-17 (5HT17). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F. Subtypes within the SR-2 group include SR-2A, -2B and -2C. Subtypes within the SR-5 group include SR-5A and -5B. SR receptors can couple to G proteins that act on either adenylate cyclase or phospholipase C (PLC). The SR-3 class of receptors are ion channels.32234.

    Pathways

    Signalistation JAK/STAT
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