Serotonin Receptor 5A anticorps (AA 1-110)
Aperçu rapide pour Serotonin Receptor 5A anticorps (AA 1-110) (ABIN1386672)
Antigène
Voir toutes Serotonin Receptor 5A (HTR5A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-110
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Réactivité croisée
- Rat
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Homologie
- Human,Mouse
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human 5HT5A receptor/SR-5A
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Isotype
- IgG
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Indications d'application
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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: "Role of peripheral 5-HT5A receptors in 5-HT-induced cardiac sympatho-inhibition in type 1 diabetic rats." dans: Scientific reports, Vol. 10, Issue 1, pp. 19358, (2021) (PubMed).
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: "Role of peripheral 5-HT5A receptors in 5-HT-induced cardiac sympatho-inhibition in type 1 diabetic rats." dans: Scientific reports, Vol. 10, Issue 1, pp. 19358, (2021) (PubMed).
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- Serotonin Receptor 5A (HTR5A)
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Autre désignation
- 5HT5A receptor/SR-5A
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Sujet
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Synonyms: HTR5A, 5 HT 5A, 5 hydroxytryptamine 5A receptor, 5-HT-5, 5-HT-5A, 5-HT5A, 5-hydroxytryptamine receptor 5A, 5HT5A, 5HT5A_HUMAN, HTR5A, Serotonin receptor 5A.
Background: SR-5B, also designated 5-hydroxytryptamine (serotonin) receptor 5B (5-HT5B) and G protein-coupled receptor 134 (GPR134) is a receptor for the monoamine ligand serotonin (5-hydroxytryptamine, 5-HT). Serotonin is a neurotransmitter derived from serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract. Serotonin actions are mediated by receptors that influence the biochemistry of depression, anxiety, sexuality and appetite. Rat SR-5B is present in serotonergic neurons in dorsal raphe (DR) and central superior nucleus (CS, median raphe nucleus). DR cell bodies showing SR-5B mRNA expression are abundant in the medial portions of the nucleus. CS coexpression of SR-5B receptor mRNA with serotonin transporter mRNA is high in the intermediate portions of the nucleus. Serotonin receptors include SR-17 (5HT17). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F. Subtypes within the SR-2 group include SR-2A, -2B and -2C. Subtypes within the SR-5 group include SR-5A and -5B. SR receptors can couple to G proteins that act on either adenylate cyclase or phospholipase C (PLC). The SR-3 class of receptors are ion channels.32234.
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Pathways
- Signalistation JAK/STAT
Antigène
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