Serotonin Receptor 5A anticorps (AA 1-110)

N° du produit ABIN1386672

Détail du produit anti-Serotonin Receptor 5A anticorps

Antigène: Serotonin Receptor 5A (HTR5A)

Épitope: AA 1-110

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 5A est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Rat

Homologie: Human,Mouse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human 5HT5A receptor/SR-5A

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Serotonin Receptor 5A (ABIN1386672)

García-Pedraza, Hernández-Abreu, Morán, Carretero, García-Domingo, Villalón: "Role of peripheral 5-HT5A receptors in 5-HT-induced cardiac sympatho-inhibition in type 1 diabetic rats." dans: Scientific reports, Vol. 10, Issue 1, pp. 19358, (2021) (PubMed).

Détails sur Serotonin Receptor 5A

Antigène: Serotonin Receptor 5A (HTR5A)

Autre désignation: 5HT5A receptor/SR-5A (HTR5A Produits)

Synonymes: anticorps HTR5A, anticorps si:dkey-265a7.5, anticorps Htr5, anticorps 5-HT5A, anticorps 5HT5A, anticorps MR22, anticorps 5-hydroxytryptamine receptor 5A, anticorps 5-hydroxytryptamine (serotonin) receptor 5A, genome duplicate a, anticorps 5-hydroxytryptamine (serotonin) receptor 5A, anticorps HTR5A, anticorps htr5aa, anticorps Htr5a

Sujet:

Synonyms: HTR5A, 5 HT 5A, 5 hydroxytryptamine 5A receptor, 5-HT-5, 5-HT-5A, 5-HT5A, 5-hydroxytryptamine receptor 5A, 5HT5A, 5HT5A_HUMAN, HTR5A, Serotonin receptor 5A.

Background: SR-5B, also designated 5-hydroxytryptamine (serotonin) receptor 5B (5-HT5B) and G protein-coupled receptor 134 (GPR134) is a receptor for the monoamine ligand serotonin (5-hydroxytryptamine, 5-HT). Serotonin is a neurotransmitter derived from serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract. Serotonin actions are mediated by receptors that influence the biochemistry of depression, anxiety, sexuality and appetite. Rat SR-5B is present in serotonergic neurons in dorsal raphe (DR) and central superior nucleus (CS, median raphe nucleus). DR cell bodies showing SR-5B mRNA expression are abundant in the medial portions of the nucleus. CS coexpression of SR-5B receptor mRNA with serotonin transporter mRNA is high in the intermediate portions of the nucleus. Serotonin receptors include SR-17 (5HT17). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F. Subtypes within the SR-2 group include SR-2A, -2B and -2C. Subtypes within the SR-5 group include SR-5A and -5B. SR receptors can couple to G proteins that act on either adenylate cyclase or phospholipase C (PLC). The SR-3 class of receptors are ion channels.32234.

Pathways: Signalistation JAK/STAT