HTR7 anticorps (AA 51-150)
Aperçu rapide pour HTR7 anticorps (AA 51-150) (ABIN1386673)
Antigène
Voir toutes HTR7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 51-150
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Réactivité croisée
- Souris, Rat
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Homologie
- Human
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human 5HT7 Receptor/SR-7
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- HTR7 (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7))
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Autre désignation
- 5HT7 Receptor/SR-7
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Sujet
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Synonyms: HT 7, 5 HT X, 5 hydroxytryptamine serotonin receptor 7 adenylate cyclase coupled, 5 hydroxytryptamine serotonin receptor 7, 5 hydroxytryptamine receptor 7, 5-HT-7, 5-HT-X, 5-HT7, 5-hydroxytryptamine receptor 7, 5HT7, 5HT7R_HUMAN, HTR7, Serotonin 5 HT 7 receptor, Serotonin receptor 7.
Background: Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. SR-3 is a ligand-gated ion channel, whereas all other known serotonin receptor subtypes are G protein-coupled receptors. SR-4 mediates widespread effects in central and peripheral nervous systems. SR-7 belongs to the superfamily of G protein-coupled receptors. The gene which encodes SR-7 maps to human chromosome 10q21-q24.
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ID gène
- 3363
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UniProt
- P34969
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Pathways
- Signalistation JAK/STAT
Antigène
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