FGFR1OP anticorps (AA 151-250)
Aperçu rapide pour FGFR1OP anticorps (AA 151-250) (ABIN1386812)
Antigène
Voir toutes FGFR1OP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 151-250
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Homologie
- Human,Mouse,Rat,Dog,Pig
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human FOP/FGFR1OP
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- FGFR1OP (FGFR1 Oncogene Partner (FGFR1OP))
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Autre désignation
- FGFR1OP
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Sujet
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Synonyms: FGFR1 oncogene partner, FGFR1OP, Fibroblast growth factor receptor 1 oncogene partner, FOP, FR1OP_HUMAN, OTTHUMP00000017612, OTTHUMP00000017613.
Background: FOP, is a 399 amino acid protein that localizes to the centrosome and contains one LisH domain. Expressed ubiquitously with highest expression in kidney, heart, muscle, colon, liver, testis and pancreas, FOP functions as a homodimer that interacts with EB1 and CEP350 and is essential for anchoring microtubules to centrosomes. Chromosomal aberrations that involve the FOP gene are associated with the pathogenesis of stem cell myeloproliferative disorder (MPD), a condition that is characterized by eosinophilia and myeloid hyperplasia and ultimately leads to acute myeloid leukemia. FOP is expressed as multiple isoforms that are produced by alternative splicing events.
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ID gène
- 11116
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Pathways
- M Phase, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
Antigène
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