Coagulation Factor IX anticorps

N° du produit ABIN1387087

Détail du produit anti-Coagulation Factor IX anticorps

Antigène: Coagulation Factor IX (F9)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Coagulation Factor IX est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Coagulation factor IXa heavy chain

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Coagulation Factor IX (ABIN1387087)

Yang, Bae, Jung, Park, Chung, Seok, Roh, Han, Oh, Sohn, Jeong, Cho: "Surface functionalization-specific binding of coagulation factors by zinc oxide nanoparticles delays coagulation time and reduces thrombin generation potential in vitro." dans: PLoS ONE, Vol. 12, Issue 7, pp. e0181634, (2017) (PubMed).

Détails sur Coagulation Factor IX

Antigène: Coagulation Factor IX (F9)

Autre désignation: Factor 9 (F9 Produits)

Synonymes: anticorps AA407498, anticorps AI506714, anticorps AK-3, anticorps Ak3l, anticorps Ak3l1, anticorps Akl3l, anticorps FIX, anticorps HEMB, anticorps P19, anticorps PTC, anticorps THPH8, anticorps AW111646, anticorps Cf-9, anticorps Cf9, anticorps f9, anticorps zgc:109775, anticorps fix, anticorps ptc, anticorps hemb, anticorps FIXA, anticorps zgc:136807, anticorps adenylate kinase 3, anticorps coagulation factor IX, anticorps coagulation factor IXa, anticorps coagulation factor 9, anticorps coagulation factor 9 S homeolog, anticorps Coagulation factor IX, anticorps coagulation factor IXb, anticorps Ak3, anticorps F9, anticorps f9a, anticorps f9, anticorps CpipJ_CPIJ003776, anticorps CpipJ_CPIJ009129, anticorps CpipJ_CPIJ013063, anticorps CpipJ_CPIJ013624, anticorps Tsp_01441, anticorps f9.S, anticorps fa9, anticorps f9b

Sujet:

Synonyms: Christmas Disease, Christmas factor, Coagulant factor IX, Coagulation factor 9, Coagulation factor IX plasma thromboplastic component, Coagulation factor IX, Coagulation factor IXa heavy chain, F9, FA9_HUMAN, Factor 9, Factor IX Deficiency, Factor9, FactorIX, FIX, GLA domain, Haemophilia B, MGC129641, MGC129642, P19 antibody Plasma thromboplastic component, Plasma thromboplastin component, PTC, Truncated coagulation factor IX.

Background: Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (prothrombin, and factors X, IX, V, and VIII), which are involved in a blood coagulation cascade that leads to the formation of insoluble fibrin clots and the promotion of platelet aggregation (1-3). Coagulation factor IX (plasma thromboplastic component, F9, F.IX, HEMB) is a vitamin K-dependent, single chain serine protease that is synthesized in the liver and circulates as an inactive precursor (3,4). Factor XIa mediated proteolytic cleavage of factor IX generates factor IXa, an active serine protease composed of a 145 amino acid light chain and a 236 amino acid catalytic heavy chain, linked through disulfide bonds (5). Genetic alterations at the Factor IX locus such as point mutations, insertions and deletions, can lead to hemophilia B, also known as Christmas disease (6).

ID gène: 2158