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FEZ1 anticorps

FEZ1 Reactivité: Humain, Rat, Souris WB, IF (p), IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1387129
  • Antigène Voir toutes FEZ1 Anticorps
    FEZ1 (Fasciculation and Elongation Protein zeta 1 (Zygin I) (FEZ1))
    Reactivité
    Humain, Rat, Souris
    Hôte
    • 25
    • 2
    • 1
    Lapin
    Clonalité
    • 28
    Polyclonal
    Conjugué
    • 10
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FEZ1 est non-conjugé
    Application
    • 23
    • 12
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human FEZ1
    Isotype
    IgG
    Top Product
    Discover our top product FEZ1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    FEZ1 (Fasciculation and Elongation Protein zeta 1 (Zygin I) (FEZ1))
    Autre désignation
    FEZ1 (FEZ1 Produits)
    Synonymes
    anticorps UNC-76, anticorps UNC76, anticorps wu:fj14c12, anticorps zgc:73258, anticorps fez1, anticorps xfez1, anticorps fasciculation and elongation protein zeta 1, anticorps fasciculation and elongation protein zeta 1 (zygin I), anticorps fasciculation and elongation protein zeta 1 L homeolog, anticorps FEZ1, anticorps Fez1, anticorps fez1, anticorps fez1.L
    Sujet

    Synonyms: Fasciculation and elongation protein zeta 1, Fasciculation and elongation protein zeta-1, Fez 1, Fez, Fez-like zinc finger protein, FEZ1, FEZ1_HUMAN, Fezl, Forebrain embryonic zinc-finger like protein, Zpf312, Zygin 1, Zygin I, Zygin-1, Zygin1, ZyginI.

    Background: Frequent loss of heterozygosity (LOH) at human chromosome 8p22-p21 is associated with various tumors including prostate and breast cancer. The 8p22-p21 region contains the FEZ1 gene, which is altered in tumors of the esophagus, prostate and breast. The FEZ1 protein (also known as leucine zipper putative tumor suppressor or LZTS1) contains a DNA-binding leucine zipper motif. FEZ1 is expressed in normal breast and prostate, but alterations in FEZ1 expression result in abnormal cell growth. The absence of FEZ1 expression is characteristic of breast and prostate cancer cell lines as well as primary breast and pro-state tumors. This absence of FEZ1 may be due to several factors, including mutations in the FEZ1 gene or hypermethylation of the CpG island flanking the FEZ1 promoter region. FEZ1 acts as a negative regulator of cell growth. During cell-cycle progression, FEZ1 localizes to microtubule components and is hyperphosphorylated by cAMP-dependent kinase.

    ID gène
    9638
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