FEZ1 anticorps (C-Term)

N° du produit ABIN6990766

Détail du produit anti-FEZ1 anticorps

Antigène: FEZ1 (Fasciculation and Elongation Protein zeta 1 (Zygin I) (FEZ1))

Épitope: AA 270-320, C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FEZ1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: FEZ1 Antibody is affinity chromatography purified via peptide column.

Immunogène: FEZ1 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human FEZ1. The immunogen is located within amino acids 270 - 320 of FEZ1.

Isotype: IgG

Information d'application

Indications d'application: FEZ1 antibody can be used for the detection of FEZ1 by Western blot at 0.5 - 1 μ,g/mL. Despite its predicted molecular weight, FEZ1 will often run at higher molecular weight in SDS-PAGE.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: FEZ1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: FEZ1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur FEZ1

Antigène: FEZ1 (Fasciculation and Elongation Protein zeta 1 (Zygin I) (FEZ1))

Autre désignation: FEZ1 (FEZ1 Produits)

Synonymes: anticorps UNC-76, anticorps UNC76, anticorps wu:fj14c12, anticorps zgc:73258, anticorps fez1, anticorps xfez1, anticorps fasciculation and elongation protein zeta 1, anticorps fasciculation and elongation protein zeta 1 (zygin I), anticorps fasciculation and elongation protein zeta 1 L homeolog, anticorps FEZ1, anticorps Fez1, anticorps fez1, anticorps fez1.L

Sujet: FEZ1 Antibody: Similar to its C. elegans homolog UNC-76, mammalian FEZ1, an abundant membrane protein and protein kinase C (PKC)-Z substrate, is involved in axonal guidance. Following phosphorylation by PKC-Z, FEZ1 translocates from the plasma membrane to the cytoplasm. FEZ1 is then able to interact with a number of proteins involved in axonal outgrowth and cellular transport such as DISC1, a candidate gene for schizophrenia, as well as kinesin-1, a microtubule-based motor protein. FEZ1 also interacts with proteins involved in transcriptional regulation and chromatin remodeling, suggesting that FEZ1 may have nuclear regulatory functions in addition to those for neuronal development. At least two distinct isoforms of FEZ1 are known to exist.

Poids moléculaire: Predicted: 42 kDa

Observed: 46 kDa

ID gène: 9638

UniProt: Q99689