SLIT1 anticorps (AA 455-500)

N° du produit ABIN1387455

Détail du produit anti-SLIT1 anticorps

Antigène: SLIT1 (Slit Homolog 1 (SLIT1))

Épitope: AA 455-500

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLIT1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Slit1/MEGF4

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur SLIT1

Antigène: SLIT1 (Slit Homolog 1 (SLIT1))

Autre désignation: Slit1/MEGF4 (SLIT1 Produits)

Synonymes: anticorps Slil1, anticorps mKIAA0813, anticorps MEGF4, anticorps SLIL1, anticorps SLIT-1, anticorps SLIT3, anticorps megf4, anticorps slil1, anticorps slit-1, anticorps SLIT1, anticorps slit3, anticorps slit homolog 1 (Drosophila), anticorps slit guidance ligand 1, anticorps slit guidance ligand 1 S homeolog, anticorps slit homolog 1 protein, anticorps slit homolog 1b (Drosophila), anticorps slit homolog 1a (Drosophila), anticorps Slit1, anticorps SLIT1, anticorps slit1.S, anticorps slit1, anticorps LOC100459557, anticorps slit1b, anticorps slit1a

Sujet:

Synonyms: MEGF 4, MEGF4, Multiple EGF like domains protein 4, Multiple epidermal growth factor like domains 4, Multiple epidermal growth factor like domains protein 4, SLIL 1, SLIL1, Slit 1, SLIT 3, Slit homolog 1, Slit homolog 1 protein, Slit-1, Slit1, SLIT3, KIAA0813, SLIT1_HUMAN.

Background: Secreted leucine-rich repeat-containing proteins 1-3 (Slit1-3) are secreted glycoproteins that influence axonal guidance and mediate normal neural development by acting as high-affinity signaling ligands for the repulsive guidance receptor, Roundabout (Robo) (1, 2). Within the developing central nervous system (CNS) of different vertebrate systems, Slit proteins are expressed in equivalent regions, suggesting a conserved function among vertebrate homologs (3,4). Slit is expressed in the midline of the central nervous system in both vertebrates and invertebrates, where it functions as a regulatory factor of mesodermal cell movement during gastrulation (5). Slit2 is a short range inhibitory guidance cue for retinal ganglion cell (RGC) axons that may mediate spatial progression of RGCs (6,7).

Pathways: Regulation of Cell Size