AASS anticorps (AA 878-926)

N° du produit ABIN1387634

L’anticorps Lapin Polyclonal anti-AASS a été validé pour WB, ELISA, ICC, IHC (p), IF (cc), IF (p) et IHC (fro). Il convient pour détecter AASS dans des échantillons de Souris.

Aperçu rapide pour AASS anticorps (AA 878-926) (ABIN1387634)

Antigène: AASS (Aminoadipate Semialdehyde Synthase (AASS))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AASS est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-AASS anticorps

Épitope: AA 878-926

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human LKRSDH

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur AASS

Antigène: AASS (Aminoadipate Semialdehyde Synthase (AASS))

Autre désignation: AASS/LKRSDH

Sujet:

Synonyms: Alpha aminoadipic semialdehyde synthase mitochondrial, LKR/SDH, LKRSDH, LORSDH, Lysine ketoglutarate reductase, Saccharopine dehydrogenase, AASS_HUMAN.

Background: Alpha-aminoadipic semialdehyde synthase (AASS), also designated lysine ketoglutarate reductase (LKR) or saccharopine dehydrogenase (SDH), is a 926 amino acid protein that exists as a homodimer in the mitochondria. AASS acts as a bifunctional enzyme containing the lysine alpha-ketoglutarate reductase (LKR) and saccharopine dehydrogenase activities that catalyzes the first two steps in lysine degradation. It is widely expressed with highest expression in liver and transcription of the AASS gene is induced upon starvation. Mutations in the gene encoding AASS result in various forms familial hyperlysinemias (FH), autosomal recessive disorders characterized by hyperlysinemia, lysinuria, and variable saccharopinuria. However, no adverse mental or physical effects have been found in patients with hyperlysinemia.

ID gène: 10157

Pathways: SARS-CoV-2 Protein Interactome