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GRAF anticorps (AA 1-100) (FITC)

ARHGAP26 Reactivité: Humain, Souris, Rat WB, IF (cc), IF (p) Hôte: Lapin Polyclonal FITC
N° du produit ABIN1390154
  • Antigène Voir toutes GRAF (ARHGAP26) Anticorps
    GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))
    Épitope
    • 14
    • 9
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 36
    • 3
    • 1
    Lapin
    Clonalité
    • 39
    Polyclonal
    Conjugué
    • 17
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GRAF est conjugé à/à la FITC
    Application
    • 33
    • 21
    • 18
    • 12
    • 12
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Dog,Cow,Sheep,Pig,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human GRAF1
    Isotype
    IgG
    Top Product
    Discover our top product ARHGAP26 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))
    Autre désignation
    GRAF1 (ARHGAP26 Produits)
    Synonymes
    anticorps ARHGAP26, anticorps GRAF, anticorps GRAF1, anticorps OPHN1L, anticorps OPHN1L1, anticorps 1810044B20Rik, anticorps 2610010G17Rik, anticorps 4933432P15Rik, anticorps AI853435, anticorps mKIAA0621, anticorps Rho GTPase activating protein 26, anticorps ARHGAP26, anticorps Arhgap26
    Sujet

    Synonyms: arhgap 26, ARHGAP26, FLJ42530, GRAF, GRAF1, GTPase regulator associated with focal adhesion kinase, GTPase regulator associated with focal adhesion kinase pp125FAK, KIAA0621, oligophrenin 1 like protein, Oligophrenin-1-like protein, oligophrenin1like protein, OPHN1L, OPHN1L1, RHG26_HUMAN, Rho GTPase activating protein 26, Rho GTPase activating protein26, Rho GTPase-activating protein 26, Rho-type GTPase-activating protein 26.

    Background: Cellular signaling by G-proteins is down-regulated by GTPase-activating proteins (GAPs), which increase the rate of GTP hydroylsis. The GTPase regulator associated with focal adhesion kinase (GRAF) has GAP activity toward Rho A and Cdc42, but not Rac1. GRAF is ubiquitously expressed with high levels in heart and brain. Expression of GRAF causes clearing of stress fibers and formation of long actin based filopodial-like extensions. Fusion of MLL with GRAF, MLL/GRAF, is included in a rare genetic subgroup of acute myeloid leukemia (AML) cases.

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