SLK anticorps (AA 885-931) (AbBy Fluor® 647)

N° du produit ABIN1391544

Cet anticorps anti-SLK est un anticorps Lapin Polyclonal détectant SLK dans WB, IF (cc) et IF (p). Adapté pour Humain.

Aperçu rapide pour SLK anticorps (AA 885-931) (AbBy Fluor® 647) (ABIN1391544)

Antigène: SLK (STE20-Like Kinase (SLK))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLK est conjugé à/à la AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-SLK anticorps (AbBy Fluor® 647)

Épitope: AA 885-931

Homologie: Human,Mouse,Rat,Dog,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SLK

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SLK

Antigène: SLK (STE20-Like Kinase (SLK))

Autre désignation: STK2

Sujet:

Synonyms: CTCL tumor antigen se20 9, LOSK, se20 9, Serine/threonine protein kinase 2, STK2, SLK, SNF1 sucrose nonfermenting like kinase, STE20 like serine/threonine-protein kinase, STE20 related kinase, STK2, SLK_HUMAN.

Background: SLK is a member of the serine/threonine kinase subfamily, Ste20. This subfamily is comprised of several mammalian kinases which exhibit sequence similarity to the Saccharomyces cerevisiae serine/threonine kinase Ste20, a protein involved in relaying signals from G protein-coupled receptors to cytosolic MAP kinase cascades. Members of this subfamily include KHS, GLK, YSK1, HPK1, Krs-1, Krs-2, GC kinase, HGK and SLK. SLK is a ubiquitously expressed protein that localizes to the cytoplasm and contains an N-terminal protein kinase domain, a central coiled-coil domain and a C-terminal ATH domain. SLK is activated through cleavage by caspase-3. SLK indirectly associates with microtubules and plays an important role in cellular stress, cell motility, cell death and cytoskeletal dynamics.

UniProt: Q9H2G2