CDKL5 anticorps (AA 401-500) (AbBy Fluor® 555)

N° du produit ABIN1391861

L’anticorps Lapin Polyclonal anti-CDKL5 a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter CDKL5 dans des échantillons de Humain.

Aperçu rapide pour CDKL5 anticorps (AA 401-500) (AbBy Fluor® 555) (ABIN1391861)

Antigène: CDKL5 (Cyclin-Dependent Kinase-Like 5 (CDKL5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDKL5 est conjugé à/à la AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-CDKL5 anticorps (AbBy Fluor® 555)

Épitope: AA 401-500

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CDKL5

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CDKL5

Antigène: CDKL5 (Cyclin-Dependent Kinase-Like 5 (CDKL5))

Autre désignation: CDKL5

Sujet:

Synonyms: Cdkl5, CDKL5_HUMAN, Cyclin dependent kinase 5 transcript, Cyclin-dependent kinase-like 5, EIEE2, ISSX, Serine/threonine kinase 9, Serine/threonine-protein kinase 9, Stk9.

Background: Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin-dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. CDKL5 (cyclin-dependent kinase-like 5) is a 1030 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family. Expressed in brain, lung, kidney, prostate, ovary, placenta, pancreas and testis, CDKL5 is thought to play a role in cell cycle regulation. Defects in CDKL5 are a cause of several disorders, such as X-linked infantile spasm syndrome and Rett syndrome.

Pathways: Regulation of Cell Size