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GLIS2 anticorps (AA 271-350) (Biotin)

GLIS2 Reactivité: Rat, Souris WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1392031
  • Antigène Voir toutes GLIS2 Anticorps
    GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))
    Épitope
    • 14
    • 7
    • 7
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 271-350
    Reactivité
    • 24
    • 18
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Rat, Souris
    Hôte
    • 38
    Lapin
    Clonalité
    • 38
    Polyclonal
    Conjugué
    • 12
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GLIS2 est conjugé à/à la Biotin
    Application
    • 34
    • 19
    • 13
    • 13
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Souris, Rat
    Homologie
    Human,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human GLIS2
    Isotype
    IgG
    Top Product
    Discover our top product GLIS2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))
    Autre désignation
    GLIS2 (GLIS2 Produits)
    Synonymes
    anticorps glis2b, anticorps nkl-A, anticorps xNKLb, anticorps NKL, anticorps NPHP7, anticorps Gli5, anticorps Klf16, anticorps Nkl, anticorps glis2a, anticorps nphp7, anticorps GLIS family zinc finger 2 L homeolog, anticorps GLIS family zinc finger 2, anticorps GLIS family zinc finger 2 S homeolog, anticorps glis2.L, anticorps GLIS2, anticorps Glis2, anticorps glis2.S
    Sujet

    Synonyms: NPHP7, NKL, GLI kruppel family member 2, GLI similar 2, GLI-similar 2, GLIS 2, GLIS family zinc finger 2, glis2, GLIS2_HUMAN, Kruppel like zinc finger protein GLIS2, Neuronal Krueppel-like protein, Tax helper protein, THP, Zinc finger protein GLI2, Zinc finger protein GLIS2.

    Background: GLIS2 is a 524 amino acid protein that belongs to the GLI C2H2-type zinc-finger protein family. By recruiting the corepressors CtBP1 and HDAC3, GLIS2 represses the transcriptional activation mediated by a??-catenin in the Wnt pathway. GLIS2 can act either as a transcription repressor or as a transcription activator and may be involved in neuron differentiation. Mutations of GLIS2 may be associated with development of progressive chronic kidney disease with characteristics resembling nephronophthisis. GLIS2 contains five tandem Cys(2)-His(2) zinc finger motifs that exhibit the highest homology to those of members of the GLI and Zic subfamilies of Kr??ppel-like proteins. GLIS2 is expressed at high levels in kidney and at low levels in heart, lung and placenta.

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