COQ10B anticorps (AA 38-110) (AbBy Fluor® 350)

N° du produit ABIN1392561

Cet anticorps anti-COQ10B est un anticorps Lapin Polyclonal détectant COQ10B dans WB, IF (cc) et IF (p). Adapté pour Humain et Souris.

Aperçu rapide pour COQ10B anticorps (AA 38-110) (AbBy Fluor® 350) (ABIN1392561)

Antigène: COQ10B (Coenzyme Q10 Homolog B (COQ10B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COQ10B est conjugé à/à la AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-COQ10B anticorps (AbBy Fluor® 350)

Épitope: AA 38-110

Specificité: Cross-reactivity with COQ10A (91 % homology with the immunogen sequence),

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human COQ10B

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur COQ10B

Antigène: COQ10B (Coenzyme Q10 Homolog B (COQ10B))

Autre désignation: COQ10B

Sujet:

Synonyms: Coenzyme Q10, Coenzyme Q10 B, Coenzyme Q10 homolog B, Coenzyme Q10B, CQ10B_HUMAN.

Background: COQ10B, Coenzyme Q10, is a 247 amino acid protein encoded by the human gene COQ10B. COQ10B is a mitochondrial protein that belongs to the COQ10 family. COQ10B is an essential biological cofactor which increases brain mitochondrial concentration and exerts neuroprotective effects. Plasma COQ10B levels decrease in patients with advanced chronic heart failure (CHF) while COQ10B levels in hyperthyroid patients are found among the lowest detected in human diseases. Likewise, COQ10B is elevated in hypothyroid subjects, also in subclinical conditions, suggesting the usefulness of this index in assessing metabolic status in thyroid disorders. It is believed that secretion of adrenal hormones is in some way related to COQ10B levels, both in augmented and reduced conditions. However, since thyroid hormones have an important role in modulating COQ10B levels and metabolism, when coexistent, thyroid deficiency seems to play a prevalent role in comparison with adrenal deficiency.

ID gène: 80219

UniProt: Q9H8M1