AKR7A2 anticorps (AA 81-150) (Biotin)

N° du produit ABIN1392859

Cet anticorps Lapin Polyclonal détecte spécifiquement AKR7A2 dans ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour AKR7A2 anticorps (AA 81-150) (Biotin) (ABIN1392859)

Antigène: AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKR7A2 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-AKR7A2 anticorps (Biotin)

Épitope: AA 81-150

Homologie: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human AKR7A2

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur AKR7A2

Antigène: AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

Autre désignation: SSA reductase/AKR7A2

Sujet:

Synonyms: AFAR, AFAR1, AFB1 aldehyde reductase 1, AFB1 AR1, AFB1-AR 1, AFB1AR1, Aflatoxin aldehyde reductase, Aflatoxin B1 aldehyde reductase member 2, Aflatoxin beta1 aldehyde reductase, Aiar, AKR7, Akr7a2, Aldo keto reductase family 7, Aldo keto reductase family 7 member A2 aflatoxin aldehyde reductase, Aldo keto reductase family 7 member A2, Aldoketoreductase 7, ARK72_HUMAN, SSA reductase, SSA reductase, Succinic semialdehyde reductase.

Background: The aldo-keto reductase 7 (AKR7) family includes AKR7A2, AKR7A3 and AKR7A4 in human, AKR7A5 in mouse and AKR7A2 in rat, all of which function in the metabolism of aflatoxin B(1) and other dicarbonyl-containing compounds. More specifically, AKR7A proteins are involved in the metabolism of compounds with ketone groups on adjacent carbon atoms in a broad range of tissues, notably the liver. The human AKR7A2 gene maps to human chromosome 1p35-36, a region frequently deleted in sporadic colorectal cancer. The functional significance of this correlation lies in the constitutive expression of AKR7A2 in human liver to eliminate aflatoxin (an environmental carcinogen), thus acting as an endogenous chemo-preventative agent.