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CADPS anticorps (AA 151-250) (Biotin)

CADPS Reactivité: Humain IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1393471
  • Antigène Voir toutes CADPS Anticorps
    CADPS (Ca++-Dependent Secretion Activator (CADPS))
    Épitope
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-250
    Reactivité
    • 13
    • 8
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 13
    • 1
    Lapin
    Clonalité
    • 14
    Polyclonal
    Conjugué
    • 13
    • 1
    Cet anticorp CADPS est conjugé à/à la Biotin
    Application
    • 11
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CAPS1
    Isotype
    IgG
    Top Product
    Discover our top product CADPS Anticorps primaire
  • Indications d'application
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    CADPS (Ca++-Dependent Secretion Activator (CADPS))
    Autre désignation
    CAPS1 (CADPS Produits)
    Synonymes
    anticorps CADPS1, anticorps CAPS, anticorps CAPS1, anticorps Caps, anticorps Caps1, anticorps Caps2, anticorps AU067781, anticorps mKIAA1121, anticorps CADPS, anticorps cadps, anticorps MGC122552, anticorps CAPS-1, anticorps caps, anticorps caps1, anticorps si:busm1-1i3.1, anticorps si:busm1-6a2.7, anticorps si:dz6a2.7, anticorps calcium dependent secretion activator, anticorps Ca2+-dependent secretion activator, anticorps Ca2+-dependent activator protein for secretion b, anticorps Ca2+ dependent secretion activator, anticorps Ca2+ dependent secretion activator L homeolog, anticorps Ca2+-dependent activator protein for secretion a, anticorps CADPS, anticorps Cadps, anticorps cadpsb, anticorps cadps, anticorps cadps.L, anticorps cadpsa
    Sujet

    Synonyms: Cadps, CADPS1, Calcium dependent secretion activator 1, Calcium-dependent activator protein for secretion 1, Calcium-dependent secretion activator 1, Caps, CAPS-1, rCAPS, CAPS1_HUMAN.

    Background: Calcium-dependent secretion activators (CAPS-1 and CAPS-2) are calcium-binding proteins that direct neurotransmitter and neuropeptide-filled vesicles to the cell membrane for secretory granule exocytosis. Both CAPS-1 and CAPS-2 are expressed primarily in the brain where they regulate the secretion of various substances. The CAPS proteins contain a PH domain that is essential for regulation of exocytosis, as well as regulation of phospholipid binding. Through their regulation of neurotrophin release from granule cells, CAPS proteins help to regulate cell fate during neuronal development. CAPS-1 is thought to regulate catecholamine release from neuronal cells, while CAPS-2 is thought to regulate release of both brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) from granule cells. Defects in the genes encoding CAPS-1 and CAPS-2 are implicated in impaired cerebral development and autism.

    Pathways
    Synaptic Vesicle Exocytosis
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