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CADPS anticorps (N-Term)

CADPS Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p), IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6990891
  • Antigène Voir toutes CADPS Anticorps
    CADPS (Ca++-Dependent Secretion Activator (CADPS))
    Épitope
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 90-140, N-Term
    Reactivité
    • 13
    • 7
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 13
    • 1
    Lapin
    Clonalité
    • 14
    Polyclonal
    Conjugué
    • 12
    • 1
    • 1
    Cet anticorp CADPS est non-conjugé
    Application
    • 10
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Specificité
    Numerous isoforms of CAPS1 are known to exist. This CAPS1 antibody is predicted to be specific to CAPS1 and not recognize CAPS2.
    Purification
    CAPS1 Antibody is affinity chromatography purified via peptide column.
    Immunogène
    CAPS1 antibody was raised against a 21 amino acid synthetic peptide near the amino terminus of the human CAPS1. The immunogen is located within amino acids 90 - 140 of CAPS1.
    Isotype
    IgG
    Top Product
    Discover our top product CADPS Anticorps primaire
  • Indications d'application
    CAPS1 antibody can be used for detection of CAPS1 by Western blot at 0.25 - 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    CAPS1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    CAPS1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    CADPS (Ca++-Dependent Secretion Activator (CADPS))
    Autre désignation
    CAPS1 (CADPS Produits)
    Synonymes
    anticorps CADPS1, anticorps CAPS, anticorps CAPS1, anticorps Caps, anticorps Caps1, anticorps Caps2, anticorps AU067781, anticorps mKIAA1121, anticorps CADPS, anticorps cadps, anticorps MGC122552, anticorps CAPS-1, anticorps caps, anticorps caps1, anticorps si:busm1-1i3.1, anticorps si:busm1-6a2.7, anticorps si:dz6a2.7, anticorps calcium dependent secretion activator, anticorps Ca2+-dependent secretion activator, anticorps Ca2+-dependent activator protein for secretion b, anticorps Ca2+ dependent secretion activator, anticorps Ca2+ dependent secretion activator L homeolog, anticorps Ca2+-dependent activator protein for secretion a, anticorps CADPS, anticorps Cadps, anticorps cadpsb, anticorps cadps, anticorps cadps.L, anticorps cadpsa
    Sujet
    CAPS1 Antibody: CAPS1 and its related protein CAPS2 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles, CAPS-deficienct neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. CAPS1 acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4, 5-bisphosphate and is thought to be a specific regulator of large dense-core vesicle fusion.
    ID gène
    8618
    NCBI Accession
    NP_899631
    UniProt
    Q9ULU8
    Pathways
    Synaptic Vesicle Exocytosis
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