DDX3X anticorps (pThr322) (Biotin)

N° du produit ABIN1395685

Cet anticorps Lapin Polyclonal détecte spécifiquement DDX3X dans WB, ELISA, IHC (p) et IHC (fro). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour DDX3X anticorps (pThr322) (Biotin) (ABIN1395685)

Antigène: DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDX3X est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-DDX3X anticorps (Biotin)

Épitope: pThr322

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human DDX3 around the phosphorylation site of Thr322

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur DDX3X

Antigène: DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))

Autre désignation: DDX3

Sujet:

Synonyms: p-DDX3 phospho T322, ATP dependent RNA helicase DDX3X, ATP-dependent RNA helicase DDX3X, CAP Rf, DBX, DDX14, DDX3X, DDX3X_HUMAN, DEAD Asp Glu Ala Asp box polypeptide 3 X linked, DEAD box, DEAD box protein 3, DEAD box protein 3 X-chromosomal, DEAD box X isoform, DEAD/H Asp Glu Ala Asp/His box polypeptide 3, DEAD/H box 3, Fibroblast Growth Factor Inducible 14, Fin14, Helicase like protein 2, Helicase-like protein 2, HLP2, X isoform, X-chromosomal.

Background: DDX3 is involved in RNA metabolism. Two DDX3 paralogs are found in humans, DDX3X is encoded by a gene found on the X chromosome while DDX3Y is encoded by a gene on the Y chromosome. DDX3Y is exclusively expressed in testis and is required for normal spermatogenesis. DDX3X is ubiquitously expressed and predominantly localizes to the nuclear speckles, participating in RNA splicing, transcription, translation initiation, mRNA transport and cell cycle regulation. DDX3X also partakes in HIV-1 replication and hepatitis C viral infections.

ID gène: 1654

Pathways: Ribonucleoprotein Complex Subunit Organization, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Ribosome Assembly