FGFR1OP anticorps (AA 151-250) (AbBy Fluor® 350)

N° du produit ABIN1398537

Cet anticorps anti-FGFR1OP est un anticorps Lapin Polyclonal détectant FGFR1OP dans WB, IF (cc) et IF (p). Adapté pour Humain.

Aperçu rapide pour FGFR1OP anticorps (AA 151-250) (AbBy Fluor® 350) (ABIN1398537)

Antigène: FGFR1OP (FGFR1 Oncogene Partner (FGFR1OP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGFR1OP est conjugé à/à la AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-FGFR1OP anticorps (AbBy Fluor® 350)

Épitope: AA 151-250

Homologie: Human,Mouse,Rat,Dog,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FOP/FGFR1OP

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur FGFR1OP

Antigène: FGFR1OP (FGFR1 Oncogene Partner (FGFR1OP))

Autre désignation: FGFR1OP

Sujet:

Synonyms: FGFR1 oncogene partner, FGFR1OP, Fibroblast growth factor receptor 1 oncogene partner, FOP, FR1OP_HUMAN, OTTHUMP00000017612, OTTHUMP00000017613.

Background: FOP, is a 399 amino acid protein that localizes to the centrosome and contains one LisH domain. Expressed ubiquitously with highest expression in kidney, heart, muscle, colon, liver, testis and pancreas, FOP functions as a homodimer that interacts with EB1 and CEP350 and is essential for anchoring microtubules to centrosomes. Chromosomal aberrations that involve the FOP gene are associated with the pathogenesis of stem cell myeloproliferative disorder (MPD), a condition that is characterized by eosinophilia and myeloid hyperplasia and ultimately leads to acute myeloid leukemia. FOP is expressed as multiple isoforms that are produced by alternative splicing events.

ID gène: 11116

Pathways: M Phase, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome