OSTM1 anticorps (AA 21-120) (Biotin)

N° du produit ABIN1399441

Cet anticorps Lapin Polyclonal détecte spécifiquement OSTM1 dans WB, ELISA, IHC (fro) et IHC (p). Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour OSTM1 anticorps (AA 21-120) (Biotin) (ABIN1399441)

Antigène: OSTM1 (Osteopetrosis Associated Transmembrane Protein 1 (OSTM1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OSTM1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-OSTM1 anticorps (Biotin)

Épitope: AA 21-120

Réactivité croisée: Humain, Souris, Rat

Homologie: Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human OSTM1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur OSTM1

Antigène: OSTM1 (Osteopetrosis Associated Transmembrane Protein 1 (OSTM1))

Autre désignation: OSTM1

Sujet:

Synonyms: GL, GIPN, OPTB5, HSPC019, Osteopetrosis-associated transmembrane protein 1, Chloride channel 7 beta subunit, OSTM1, UNQ6098/PRO21201

Background: OSTM1 (osteopetrosis associated transmembrane protein 1), also known as gl (gray-lethal) or HSPC019, is a 338 amino acid single-pass type I membrane protein that is expressed primarily in osteoclasts and melanocytes as well as brain, kidney and spleen. Bone autosomal recessive osteopetrosis (ARO) is the most severe form of hereditary bone disease whose cellular basis is in the osteoclast and is characterized by abnormally dense bone, due to defective resorption of immature bone. ARO is suggested to be caused by mutations in the OSTM1 gene. The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. Defects in the OSTM1 gene are also the cause of the spontaneous gl mutant, which is responsible for a coat color defect in mice.

ID gène: 28962

UniProt: Q86WC4