CDK5RAP1 anticorps (Biotin)
Aperçu rapide pour CDK5RAP1 anticorps (Biotin) (ABIN1400695)
Antigène
Voir toutes CDK5RAP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Réactivité croisée
- Humain, Souris, Rat
-
Purification
- Purified by Protein A.
-
Immunogène
- KLH conjugated synthetic peptide derived from human CDK5RAP1
-
Isotype
- IgG
-
-
-
-
Indications d'application
-
WB 1:300-5000
IHC-P 1:200-400 -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 μg/μL
-
Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C for 12 months.
-
Date de péremption
- 12 months
-
-
- CDK5RAP1 (CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1))
-
Autre désignation
- CDK5RAP1
-
Sujet
-
Synonyms: CDK5 activator binding protein C42 like, CDK5 regulatory subunit associated protein 1, CDK5RAP1.3, CDK5RAP1.4, CGI 05, HSPC167, C20orf34 antibody C42, CDK5 activator binding protein C42, CK5P1_HUMAN.
Background: Cyclin dependent kinase 5 (Cdk5) is a key regulator of cell cycle progression in neuronal differentiation that physically associates with and is activated by the neuron-specific protein p35. CDK5RAP1 (Cdk5 regulatory subunit-associated protein 1), also known as Cdk5 activator-binding protein C42, is a 601 amino acid protein that specifically inhibits Cdk5 activation by p35 through formation of a dimer that inhibits kinase activity. CDK5RAP1 contains one TRAM domain, which is thought to bind tRNA and deliver the RNA-modifying enzymatic domain to its target. There are 4 named isoforms of CDK5RAP1 that are produced as a result of alternative splicing events and are expressed at high levels in heart and skeletal muscle.
-
ID gène
- 51654
Antigène
-