RANBP2 anticorps (AbBy Fluor® 350)

N° du produit ABIN1402059

Cet anticorps anti-RANBP2 est un anticorps Lapin Polyclonal détectant RANBP2 dans IF (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour RANBP2 anticorps (AbBy Fluor® 350) (ABIN1402059)

Antigène: RANBP2 (RAN Binding Protein 2 (RANBP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RANBP2 est conjugé à/à la AbBy Fluor® 350

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-RANBP2 anticorps (AbBy Fluor® 350)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RanBP2

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur RANBP2

Antigène: RANBP2 (RAN Binding Protein 2 (RANBP2))

Autre désignation: RanBP2

Sujet:

Synonyms: Nuclear pore complex protein Nup358, Nucleoporin 358, Nucleoporin Nup358, NUP358, P270, RAN binding protein 2, Ran-binding protein 2, RANBP2, RBP2_HUMAN, Transformation related protein 2, TRP 1, TRP 2, TRP1, TRP2, 358 kDa nucleoporin, E3 SUMO-protein ligase RanBP2.

Background: The nuclear pore complex protein, Ran-binding protein 2 (Ran BP-2 or Nup358), contains four Ran-binding domains. Ran BP-2 is a large scaffold cyclophilin-related protein expressed in photoreceptor cells. Ran BP-2 localization at cytoplasmic fibrils emanating from the nuclear pore complex and interaction with the Ran-GTPase support its role in nucleocytoplasmic transport processes. In humans, the Ran BP-2 gene is partially duplicated in a gene cluster and lies in a hot spot for recombination on chromosome 2q. This genetic heterogeneity renders further significance of this genomic region in human disease due to its possible involvement in genetically linked disorders such as juvenile nephronophthisis, congenital hepatic fibrosis and chorioretinal dysplasia.

ID gène: 5903

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus