SIRT5 anticorps (AA 120-170) (AbBy Fluor® 488)

N° du produit ABIN1402816

Cet anticorps Lapin Polyclonal détecte spécifiquement SIRT5 dans WB, FACS et IF (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour SIRT5 anticorps (AA 120-170) (AbBy Fluor® 488) (ABIN1402816)

Antigène: SIRT5 (Sirtuin 5 (SIRT5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRT5 est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-SIRT5 anticorps (AbBy Fluor® 488)

Épitope: AA 120-170

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SIRT5

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SIRT5

Antigène: SIRT5 (Sirtuin 5 (SIRT5))

Autre désignation: SIRT5

Sujet:

Synonyms: SIR2L5, NAD-dependent protein deacylase sirtuin-5, mitochondrial, Regulatory protein SIR2 homolog 5, SIR2-like protein 5, SIRT5

Background: NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Has weak NAD-dependent protein deacetylase activity, however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro.

ID gène: 23408

UniProt: Q9NXA8

Pathways: SARS-CoV-2 Protein Interactome