HEXIM1 anticorps (AbBy Fluor® 555)

N° du produit ABIN1402841

L’anticorps Lapin Polyclonal anti-HEXIM1 a été validé pour WB et IF (p). Il convient pour détecter HEXIM1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour HEXIM1 anticorps (AbBy Fluor® 555) (ABIN1402841)

Antigène: HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HEXIM1 est conjugé à/à la AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-HEXIM1 anticorps (AbBy Fluor® 555)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HEXIM1/EDG1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HEXIM1

Antigène: HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))

Autre désignation: HEXIM1

Sujet:

Synonyms: Cardiac lineage protein 1, CLP 1, CLP1, EDG 1, EDG1, Estrogen down-regulated gene 1 protein, Hexamethylene bis acetamide inducible 1, Hexamethylene bis acetamide inducible protein, Hexamethylene bis acetamide inducible transcript 1, Hexamethylene bis-acetamide-inducible protein 1, HEXI1_HUMAN, HEXIM 1, Hexim1, HEXIM1 protein, HIS 1, HIS1, HMBA inducible, MAQ 1, MAQ1, Menage a quatre 1, Menage a quatre protein 1, Protein HEXIM1.

Background: Hexamethylene bis-acetamide inducible 1 (HEXIM1) and Hexamethylene bis-acetamide inducible 2 (HEXIM2) comprise a family of proteins which inhibit positive transcription elongation factor b (P-TEFb) through association with 7SK. P-TEFb is composed of a catalytic subunit, Cdk9, and either Cyclin T1 or T2 as a regulatory subunit. This complex regulates eukaryotic gene expression at the level of elongation. The C-terminal domains of HEXIM proteins interact directly with each other. Via these domains, HEXIM1 and HEXIM2 form stable homo- and hetero-oligomers, which may aid in the formation of the 7SK small nuclear ribonucleic acid particle. Despite their similar functions, HEXIM1 and HEXIM2 exhibit distinct expression patterns in various established cell lines and human tissues.

ID gène: 10614