PDE4DIP anticorps (AbBy Fluor® 555)

N° du produit ABIN1402943

L’anticorps Lapin Polyclonal anti-PDE4DIP a été validé pour IF (p). Il convient pour détecter PDE4DIP dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PDE4DIP anticorps (AbBy Fluor® 555) (ABIN1402943)

Antigène: PDE4DIP (phosphodiesterase 4D Interacting Protein (PDE4DIP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE4DIP est conjugé à/à la AbBy Fluor® 555

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-PDE4DIP anticorps (AbBy Fluor® 555)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CMYA2/PDE4DIP

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PDE4DIP

Antigène: PDE4DIP (phosphodiesterase 4D Interacting Protein (PDE4DIP))

Autre désignation: CMYA2

Sujet:

Synonyms: Cardiomyopathy associated protein 2, Cardiomyopathy-associated protein 2, CMYA2, MMGL, MYOME_HUMAN, Myomegalin, Pde4dip, Phosphodiesterase 4D interacting protein, Phosphodiesterase 4D-interacting protein.

Background: May function as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes.Myomegalin, is a 2,346 amino acid protein that contains one NBPF domain and localizes to the nucleus, cytoplasm, centrosome and Golgi apparatus. Expressed at high levels in fetal and adult heart and at lower levels in brain and placenta, myomegalin is thought to function as an anchoring protein that sequesters members of the cAMP-dependent pathway to the Golgi and to centrosomes, thereby mediating cAMP pathway dynamics. Translocations in the gene that encodes myomegalin are associated with myeloproliferative disorders (MBDs), a group of diseases caused by an overproduction of blood cells. Myomegalin exists as twelve isoforms due to alternative splicing events.

ID gène: 9659

Pathways: SARS-CoV-2 Protein Interactome