Coagulation Factor IX anticorps (Biotin)

N° du produit ABIN1403083

Cet anticorps Lapin Polyclonal détecte spécifiquement Coagulation Factor IX dans WB et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Coagulation Factor IX anticorps (Biotin) (ABIN1403083)

Antigène: Coagulation Factor IX (F9)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Coagulation Factor IX est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Coagulation Factor IX anticorps (Biotin)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Coagulation factor IXa heavy chain

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Coagulation Factor IX

Antigène: Coagulation Factor IX (F9)

Autre désignation: Factor 9

Sujet:

Synonyms: Christmas Disease, Christmas factor, Coagulant factor IX, Coagulation factor 9, Coagulation factor IX plasma thromboplastic component, Coagulation factor IX, Coagulation factor IXa heavy chain, F9, FA9_HUMAN, Factor 9, Factor IX Deficiency, Factor9, FactorIX, FIX, GLA domain, Haemophilia B, MGC129641, MGC129642, P19 antibody Plasma thromboplastic component, Plasma thromboplastin component, PTC, Truncated coagulation factor IX.

Background: Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (prothrombin, and factors X, IX, V, and VIII), which are involved in a blood coagulation cascade that leads to the formation of insoluble fibrin clots and the promotion of platelet aggregation (1-3). Coagulation factor IX (plasma thromboplastic component, F9, F.IX, HEMB) is a vitamin K-dependent, single chain serine protease that is synthesized in the liver and circulates as an inactive precursor (3,4). Factor XIa mediated proteolytic cleavage of factor IX generates factor IXa, an active serine protease composed of a 145 amino acid light chain and a 236 amino acid catalytic heavy chain, linked through disulfide bonds (5). Genetic alterations at the Factor IX locus such as point mutations, insertions and deletions, can lead to hemophilia B, also known as Christmas disease (6).

ID gène: 2158