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C17orf64 anticorps (Biotin)

C17orf64 Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1403833
  • Antigène Tous les produits C17orf64
    C17orf64 (Chromosome 17 Open Reading Frame 64 (C17orf64))
    Reactivité
    • 22
    • 15
    • 14
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 22
    Lapin
    Clonalité
    • 22
    Polyclonal
    Conjugué
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp C17orf64 est conjugé à/à la Biotin
    Application
    • 18
    • 13
    • 5
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human C17orf64
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    C17orf64 (Chromosome 17 Open Reading Frame 64 (C17orf64))
    Autre désignation
    C17orf64 (C17orf64 Produits)
    Synonymes
    anticorps C17orf64, anticorps chromosome 17 open reading frame 64, anticorps chromosome 19 open reading frame, human C17orf64, anticorps RIKEN cDNA 1700125H20 gene, anticorps C17orf64, anticorps C19H17ORF64, anticorps C19H17orf64, anticorps 1700125H20Rik
    Sujet

    Synonyms: C17orf64, Chromosome 17 open reading frame 64, CQ064_HUMAN, Hypothetical protein LOC124773, Uncharacterized protein C17orf64.

    Background: C17orf64 is a 562 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5 % of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

    ID gène
    124773
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