HSPA4 anticorps (Biotin)

N° du produit ABIN1405051

Détail du produit anti-HSPA4 anticorps (Biotin)

Antigène: HSPA4 (Heat Shock 70kDa Protein 4 (HSPA4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSPA4 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HSP_7/cvHSP

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur HSPA4

Antigène: HSPA4 (Heat Shock 70kDa Protein 4 (HSPA4))

Autre désignation: HSP_7 (HSPA4 Produits)

Synonymes: anticorps APG-2, anticorps HS24/P52, anticorps HSPH2, anticorps RY, anticorps hsp70, anticorps hsp70RY, anticorps Hsp110, anticorps Hsp70, anticorps irp94, anticorps 70kDa, anticorps AI317151, anticorps Hsp70RY, anticorps mKIAA4025, anticorps hspa4, anticorps wu:fi30e11, anticorps zgc:55743, anticorps zgc:77413, anticorps hs24/p52, anticorps hspa4-a, anticorps osp94, anticorps pg-2, anticorps hspa4l, anticorps wu:fc41d05, anticorps wu:fi59h02, anticorps wu:fj35c08, anticorps zgc:55506, anticorps heat shock protein family A (Hsp70) member 4, anticorps heat shock protein family A member 4, anticorps heat shock protein 4, anticorps heat shock protein 4b, anticorps heat shock protein family A (Hsp70) member 4 S homeolog, anticorps heat shock protein 4a, anticorps HSPA4, anticorps Hspa4, anticorps hspa4b, anticorps hspa4.S, anticorps hspa4a

Sujet:

Synonyms: Cardiovascular heat shock protein, cvHsp, Heat shock 27kda protein family member 7, Heat shock protein beta 7, Heat shock protein beta-7, Hsp25 2, HspB7, HSPB7_HUMAN, Hypothetical protein flj34956, RP11-5P18.6

Background: The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. Heat shock proteins (also known as molecular chaperones) fall into six general families: HSP 90, HSP 70, HSP 60, the small HSPs, the immunophilins and the HSP 110 family. HSPB7 (heat shock 27 kDa protein family, member 7), also known as cvHSP (cardiovascular heat shock protein) or Heat shock protein beta-7, is a member of the small HSP (sHSP) family expressed in heart and skeletal muscle. Members of the sHSP family contain a conserved C-terminal ?crystallin domain and typically function in homo- or heteromeric complexes. The sHSPs bind to denatured proteins and are responsible for preventing the aggregation of these proteins. In response to muscle fiber transformation and in muscular dystrophy, the expression levels of HSPB7 are drastically increased, suggesting that HSPB7 may be a useful target in therapeutic strategies for preventing age-related muscle wasting.

ID gène: 27129