TMPRSS5 anticorps (AA 161-260) (HRP)

N° du produit ABIN1407662

L’anticorps Lapin Polyclonal anti-TMPRSS5 a été validé pour WB, ELISA, IHC (p) et IHC (fro). Il convient pour détecter TMPRSS5 dans des échantillons de Humain.

Aperçu rapide pour TMPRSS5 anticorps (AA 161-260) (HRP) (ABIN1407662)

Antigène: TMPRSS5 (Transmembrane Protease, serine 5 (TMPRSS5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMPRSS5 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-TMPRSS5 anticorps (HRP)

Épitope: AA 161-260

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TMPRSS5

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur TMPRSS5

Antigène: TMPRSS5 (Transmembrane Protease, serine 5 (TMPRSS5))

Autre désignation: TMPRSS5

Sujet:

Synonyms: Spinesin, TMPRSS 5, TMPRSS-5, TMPRSS5, TMPS5_HUMAN, Transmembrane protease serine 5, Transmembrane protease, serine 5 spinesin, Transmembrane protease, serine 5, MGC141886, MGC148044, OTTHUMP00000238209, OTTHUMP00000238210, OTTHUMP00000238211, OTTHUMP00000238212, OTTHUMP00000238213.

Background: Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth, allow desquamation of tumor cells into the surrounding environment, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors. TMPRSS5 (transmembrane protease, serine 5), also known as spinesin, is a 457 amino acid single-pass type II membrane protein that is expressed specifically in brain and is thought to play a role in hearing. A member of the peptidase S1 family, TMPRSS5 contains one peptidase S1 domain and an SRCR domain, and is encoded by a gene that maps to human chromosome 11q23.2. Defects in the gene encoding TMPRSS5 are associated with deafness.