OLIG2 anticorps (AA 81-180) (Cy5)

N° du produit ABIN1407724

Détail du produit anti-OLIG2 anticorps (Cy5)

Antigène: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Épitope: AA 81-180

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OLIG2 est conjugé à/à la Cy5

Application: Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Réactivité croisée: Humain, Rat

Homologie: Mouse,Dog,Cow,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human OLIG2

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur OLIG2

Antigène: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Autre désignation: OLIG2 (OLIG2 Produits)

Synonymes: anticorps olig3.2, anticorps MGC89336, anticorps OLIG2, anticorps BHLHB1, anticorps OLIGO2, anticorps PRKCBP2, anticorps RACK17, anticorps bHLHe19, anticorps wu:fc64g09, anticorps AI604895, anticorps Bhlhb1, anticorps Olg-2, anticorps Oligo2, anticorps RK17, anticorps oligodendrocyte transcription factor 4, anticorps oligodendrocyte transcription factor 2, anticorps oligodendrocyte lineage transcription factor 2, anticorps olig4, anticorps OLIG2, anticorps Olig2, anticorps olig2

Sujet:

Synonyms: Basic domain helix loop helix protein class B 1, Basic helix loop helix protein class B 1, bHLHB1, bHLHe19, Class B basic helix loop helix protein 1, Class B basic helix-loop-helix protein 1, class E basic helix loop helix protein 19, Class E basic helix-loop-helix protein 19, Human protein kinase C binding protein RACK17, Olig2, OLIG2_HUMAN, Oligo2, Oligodendrocyte lineage transcription factor 2, Oligodendrocyte specic bHLH transcription factor 2, Oligodendrocyte transcription factor 2, PRKCBP2, Protein kinase C binding protein 2, Protein kinase C binding protein RACK17, Protein kinase C-binding protein 2, Protein kinase C-binding protein RACK17, RACK17.

Background: The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3, which differ in tissue expression. OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis. OLIG2 is more widely expressed in embryonic brain than OLIG1, while OLIG3 is primarily expressed in non-neural tissues. OLIG1 and OLIG2 interact with the Nkx-2.2 homeodomain protein, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube. These interactions between OLIG proteins and Nkx-2.2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development. OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas. Therefore, OLIG proteins are candidates for molecular markers of human glial brain tumors, which are the most common primary malignancies of the human brain.