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BBS9 anticorps (AA 244-320) (Cy5)

BBS9 Reactivité: Rat IF (p), IF (cc) Hôte: Lapin Polyclonal Cy5
N° du produit ABIN1409590
  • Antigène Voir toutes BBS9 Anticorps
    BBS9 (Bardet-Biedl Syndrome 9 (BBS9))
    Épitope
    • 14
    • 8
    • 8
    • 6
    • 5
    • 1
    • 1
    • 1
    AA 244-320
    Reactivité
    • 30
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Rat
    Hôte
    • 44
    Lapin
    Clonalité
    • 44
    Polyclonal
    Conjugué
    • 11
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BBS9 est conjugé à/à la Cy5
    Application
    • 20
    • 19
    • 12
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Dog,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human BBS9
    Isotype
    IgG
    Top Product
    Discover our top product BBS9 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    BBS9 (Bardet-Biedl Syndrome 9 (BBS9))
    Autre désignation
    BBS9 (BBS9 Produits)
    Synonymes
    anticorps b1, anticorps B1, anticorps C18, anticorps D1, anticorps PTHB1, anticorps RGD1308472, anticorps E130103I17Rik, anticorps Bardet-Biedl syndrome 9, anticorps bardet-biedl syndrome 9, anticorps Bardet-Biedl syndrome 9 (human), anticorps BBS9, anticorps bbs9, anticorps Bbs9
    Sujet

    Synonyms: B1, D1, C18, PTHB1, Protein PTHB1, Bardet-Biedl syndrome 9 protein, Parathyroid hormone-responsive B1 gene protein, BBS9

    Background: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization.

    ID gène
    27241
    UniProt
    Q3SYG4
    Pathways
    Signalisation Hedgehog
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