PDE7A anticorps (Cy3)

N° du produit ABIN1409973

Cet anticorps anti-PDE7A Polyclonal Lapin conjugué à Cy3 (ABIN1409973) détecte spécifiquement PDE7A dans WB, IF et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PDE7A anticorps (Cy3) (ABIN1409973)

Antigène: PDE7A (phosphodiesterase 7A (PDE7A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE7A est conjugé à/à la Cy3

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-PDE7A anticorps (Cy3)

Fonction: PDE7A Polyclonal Antibody, Cy3 Conjugated

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PDE7A

Isotype: IgG

Information d'application

Indications d'application: WB(1:500-2000), IF(1:100-500), Flow-Cyt(1 μg/Test)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PDE7A

Antigène: PDE7A (phosphodiesterase 7A (PDE7A))

Autre désignation: Pde7a

Sujet:

Synonyms: HCP 1, HCP1, High affinity cAMP specific 3'5' cyclic phosphodiesterase 7A, High affinity cAMP-specific 3'', P2A, PDE 7, PDE 7A, PDE7, PDE71, PDE7A, PDE7A_HUMAN, Phosphodiesterase 7A, Phosphodiesterase isozyme 7, Phosphodiesterase7A, Rolipram insensitive phosphodiesterase type 7, TM 22, TM22, 5''-cyclic phosphodiesterase 7A.

Background: Phosphodiesterases (PDE, also designated cyclic nucleotide phosphodiesterase) are important for the downregulation of the intracellular level of the second messenger cyclic adenosine monophosphate (cAMP) by hydrolyzing cAMP to 5'AMP. Phosphodiesterase type 3 isoforms, PDE3A and 3B, are expressed primarily in cardiovascular tissue and adipose tissue, respectively. PDE3A, is found in myocardium and platelets and PDE3B is found in lymphocytes. The PDE7A1 (HCP1) isozyme and the PDE7A2 proteins, alternate splice products of PDE7A, are highly expressed in skeletal muscle. PDE7B is most highly expressed in pancreas. The PDE family contains proteins that serve tissue-specific roles in regulation of lipolysis, glycogenolysis, myocardial contractility, and smooth muscle relaxation.

ID gène: 5150

UniProt: Q13946

Pathways: cAMP Metabolic Process