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SH3PXD2A anticorps (AA 261-360) (Cy3)

SH3PXD2A Reactivité: Rat IF (cc), IF (p) Hôte: Lapin Polyclonal Cy3
N° du produit ABIN1410387
  • Antigène Voir toutes SH3PXD2A Anticorps
    SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))
    Épitope
    • 14
    • 12
    • 9
    • 6
    • 1
    • 1
    AA 261-360
    Reactivité
    • 31
    • 15
    • 11
    Rat
    Hôte
    • 43
    • 1
    • 1
    Lapin
    Clonalité
    • 45
    Polyclonal
    Conjugué
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SH3PXD2A est conjugé à/à la Cy3
    Application
    • 20
    • 20
    • 12
    • 12
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human FISH
    Isotype
    IgG
    Top Product
    Discover our top product SH3PXD2A Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))
    Autre désignation
    FISH (SH3PXD2A Produits)
    Synonymes
    anticorps FISH, anticorps SH3MD1, anticorps TKS5, anticorps 2310014D11Rik, anticorps AA589508, anticorps AI256723, anticorps AI413738, anticorps C230050L11, anticorps EG329070, anticorps Fish, anticorps Gm5098, anticorps Sh3md1, anticorps TSK5, anticorps Tks5, anticorps sh3pxd2a, anticorps si:dkey-82d4.2, anticorps SH3 and PX domains 2A, anticorps SH3 and PX domains 2Aa, anticorps SH3PXD2A, anticorps Sh3pxd2a, anticorps sh3pxd2aa
    Sujet

    Synonyms: Adapter protein TKS5, Five SH3 domain-containing protein, SH3 and PX domain-containing protein 2A, SH3 multiple domains protein 1, Sh3md1, Sh3pxd2a, SPD2A_HUMAN, TKs5, Tyrosine kinase substrate with five SH3 domains.

    Background: Fish, a potential Src substrate, is a broadly expressed adaptor protein containing five SH3 domains and a phox homology (PX) domain (1). The Src family of protein tyrosine kinases act in signal transduction pathways (2-4). Src kinases vary in expression but are strongly regulated in vivo, catalytic activity is repressed by interacting with the SH3 domain (5-7). In Src-transformed fibroblasts and in normal cells treated with certain growth factors fish is tyrosine-phosphorylated (1). Treatment of cells with cytochalasin D results in rapid tyrosine phosphorylation of fish, along with activation of Src (1). Fish is likely to be involved in tyrosine kinase signaling and may have a role in cytoskeletal changes (1).

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