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AKR7A2 anticorps (AA 81-150) (HRP)

AKR7A2 Reactivité: Humain ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1410752
  • Antigène Voir toutes AKR7A2 Anticorps
    AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))
    Épitope
    • 14
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 81-150
    Reactivité
    • 52
    • 17
    • 12
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 41
    • 11
    Lapin
    Clonalité
    • 43
    • 9
    Polyclonal
    Conjugué
    • 25
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp AKR7A2 est conjugé à/à la HRP
    Application
    • 24
    • 13
    • 13
    • 10
    • 9
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human AKR7A2
    Isotype
    IgG
    Top Product
    Discover our top product AKR7A2 Anticorps primaire
  • Indications d'application
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))
    Autre désignation
    SSA reductase/AKR7A2 (AKR7A2 Produits)
    Synonymes
    anticorps AFAR, anticorps AFAR1, anticorps AFB1-AR1, anticorps AKR7, anticorps Aiar, anticorps akr7a2, anticorps aldo-keto reductase family 7 member A2, anticorps aldo-keto reductase family 7, member A2, anticorps aldo-keto reductase family 7, member A2 L homeolog, anticorps AKR7A2, anticorps Akr7a2, anticorps akr7a2.L
    Sujet

    Synonyms: AFAR, AFAR1, AFB1 aldehyde reductase 1, AFB1 AR1, AFB1-AR 1, AFB1AR1, Aflatoxin aldehyde reductase, Aflatoxin B1 aldehyde reductase member 2, Aflatoxin beta1 aldehyde reductase, Aiar, AKR7, Akr7a2, Aldo keto reductase family 7, Aldo keto reductase family 7 member A2 aflatoxin aldehyde reductase, Aldo keto reductase family 7 member A2, Aldoketoreductase 7, ARK72_HUMAN, SSA reductase, SSA reductase, Succinic semialdehyde reductase.

    Background: The aldo-keto reductase 7 (AKR7) family includes AKR7A2, AKR7A3 and AKR7A4 in human, AKR7A5 in mouse and AKR7A2 in rat, all of which function in the metabolism of aflatoxin B(1) and other dicarbonyl-containing compounds. More specifically, AKR7A proteins are involved in the metabolism of compounds with ketone groups on adjacent carbon atoms in a broad range of tissues, notably the liver. The human AKR7A2 gene maps to human chromosome 1p35-36, a region frequently deleted in sporadic colorectal cancer. The functional significance of this correlation lies in the constitutive expression of AKR7A2 in human liver to eliminate aflatoxin (an environmental carcinogen), thus acting as an endogenous chemo-preventative agent.

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