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GDAP1 anticorps (AA 151-230) (Cy7)

GDAP1 Reactivité: Souris WB, IF (p), IF (cc) Hôte: Lapin Polyclonal Cy7
N° du produit ABIN1410852
  • Antigène Voir toutes GDAP1 Anticorps
    GDAP1 (Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1))
    Épitope
    • 14
    • 2
    • 2
    • 1
    • 1
    AA 151-230
    Reactivité
    • 26
    • 15
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 28
    • 1
    Lapin
    Clonalité
    • 29
    Polyclonal
    Conjugué
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GDAP1 est conjugé à/à la Cy7
    Application
    • 22
    • 12
    • 12
    • 7
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
     Réactivité croisée
    Souris
    Homologie
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human GDAP1
    Isotype
    IgG
    Top Product
    Discover our top product GDAP1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    GDAP1 (Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1))
    Autre désignation
    GDAP1 (GDAP1 Produits)
    Synonymes
    anticorps CMT4, anticorps CMT4A, anticorps CMTRIA, anticorps ganglioside induced differentiation associated protein 1, anticorps ganglioside-induced differentiation-associated-protein 1, anticorps GDAP1, anticorps Gdap1
    Sujet

    Synonyms: Ganglioside induced dferentiation associated protein 1, Ganglioside-induced dferentiation-associated protein 1, GDAP1, GDAP1_HUMAN.

    Background: Glutathione S-transferases (GSTs) function to conjugate reduced glutathione to many exogenous and endogenous hydrophobic electrophiles. Although it shares the carboxy and amino-terminal glutathione S-transferase domains, GDAP1 is characterized as a GST-like protein because it contains an extended GST domain II and a predicted transmembrane domain, two characteristics which are unusual for GST family members. GDAP1 may function in a signal transduction pathway that is responsible for ganglioside-induced neurite differentiation and also may play a role in protecting myelin membranes from free-radical damage. Mutations in the gene encoding GDAP1 is the cause of many forms of Charcot-Marie-Tooth disease, a common inherited disorder of the peripheral nervous system that is characterized by reduced nerve conduction velocities, slow progressive distal muscle atrophy and absent deep tendon reflexes.

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