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CBLN4 anticorps (AA 101-201) (Cy7)

CBLN4 Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy7
N° du produit ABIN1411386
  • Antigène Voir toutes CBLN4 Anticorps
    CBLN4 (Cerebellin 4 Precursor (CBLN4))
    Épitope
    • 14
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-201
    Reactivité
    • 31
    • 15
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 30
    • 1
    Lapin
    Clonalité
    • 31
    Polyclonal
    Conjugué
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CBLN4 est conjugé à/à la Cy7
    Application
    • 23
    • 12
    • 12
    • 10
    • 8
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CBLN4
    Isotype
    IgG
    Top Product
    Discover our top product CBLN4 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CBLN4 (Cerebellin 4 Precursor (CBLN4))
    Autre désignation
    CBLN4 (CBLN4 Produits)
    Synonymes
    anticorps zgc:172190, anticorps cerebellin-4, anticorps CBLNL1, anticorps AI848962, anticorps cerebellin 4 precursor, anticorps cerebellin 4 precursor L homeolog, anticorps cerebellin 4 precursor protein, anticorps CBLN4, anticorps cbln4, anticorps cbln4.L, anticorps Cbln4
    Sujet

    Synonyms: CBLN 4, CBLNL1, Cerebellin 4, Cerebellin 4 precursor, Cerebellin like glycoprotein 1, Cerebellin precursor like 1, Cerebellin4, CBLN4_HUMAN.

    Background: Cerebellin (CER), which was originally isolated from rat cerebellum, is a hexadecapeptide derived from a larger precursor called Cerebellin 1, also designated precerebellin 1 or Cbln1. Four propeptides, Cerebellin 1, Cerebellin 2 (Cbln2), Cerebellin 3 (Cbln3) and Cerebellin 4 (Cbln4), comprise the precerebellin subfamily within the C1q protein family. Cerebellin family members act as transneuronal regulators of synapse development and synaptic plasticity in various brain regions. Cerebellin and its metabolite, des-Ser(1)Cer, are also expressed in several extra-cerebellar tissues, including adrenal gland. Cerebellin 1, 2 and 3 assemble into homomeric and heteromeric complexes, thereby influencing each other?s degradation and secretion. Cerebellin 3 is not able to form homomeric complexes, and can only be secreted upon forming a heteromeric complex with Cerebellin 1. Decreased concentrations of Cerebellin have been found in the brain of patients with olivopontocerebellar atrophy (OPCA) and Shy-Drager syndrome, suggesting a role for Cerebellin in the pathology of these diseases.

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