TTC21B anticorps (AA 1221-1316) (HRP)

N° du produit ABIN1412870

L’anticorps anti-TTC21B Polyclonal Lapin est utilisé pour la détection de TTC21B dans des échantillons de Rat. Il a été validé pour ELISA, IHC (fro) et IHC (p).

Aperçu rapide pour TTC21B anticorps (AA 1221-1316) (HRP) (ABIN1412870)

Antigène: TTC21B (Tetratricopeptide Repeat Domain 21B (TTC21B))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TTC21B est conjugé à/à la HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TTC21B anticorps (HRP)

Épitope: AA 1221-1316

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TTC21B

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur TTC21B

Antigène: TTC21B (Tetratricopeptide Repeat Domain 21B (TTC21B))

Autre désignation: TTC21B

Sujet:

Synonyms: ATD4, JBTS11, Nbla10696, NPHP12, Putative protein product of Nbla10696, Tetratricopeptide repeat protein 21B, THM1, TPR repeat protein 21B, TT21B_HUMAN, Ttc21b.

Background: The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. TTC21B (tetratricopeptide repeat domain 21B), also known as THM1, is a 1,316 amino acid protein that contains 19 TPR repeats and belongs to the TTC21 family. Localizing to cytoplasm and cytoskeleton, TTC21B exists as two alternatively spliced isoforms and is thought to negatively regulate Shh signal transduction. TTC21B may also be involved in retrograde intraflagellar transport in cilia, and is encoded by a gene that maps to human chromosome 2q24.3.

ID gène: 79809

UniProt: Q7Z4L5

Pathways: Signalisation Hedgehog