CHST1 anticorps (AA 251-350) (HRP)

N° du produit ABIN1414809

Cet anticorps anti-CHST1 est un anticorps Lapin Polyclonal détectant CHST1 dans WB, ELISA, IHC (p) et IHC (fro). Adapté pour Souris et Rat.

Aperçu rapide pour CHST1 anticorps (AA 251-350) (HRP) (ABIN1414809)

Antigène: CHST1 (Carbohydrate (Keratan Sulfate Gal-6) Sulfotransferase 1 (CHST1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHST1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-CHST1 anticorps (HRP)

Épitope: AA 251-350

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Keratan Sulfate

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CHST1

Antigène: CHST1 (Carbohydrate (Keratan Sulfate Gal-6) Sulfotransferase 1 (CHST1))

Autre désignation: CHST1

Sujet:

Synonyms: Carbohydrate chondroitin 6 keratan sulfotransferase 1, Carbohydrate chondroitin 6 keratan sulfotransferase, Carbohydrate keratan sulfate Gal 6 sulfotransferase, Carbohydrate keratan sulfate Gal 6 sulfotransferase 1, Carbohydrate sulfotransferase 1, CHST1, EC 2.8.2.21, Galactose N acetylglucosamine N acetylglucosamine 6 O sulfotransferase 1, GST 1 antibody Keratan sulfate Gal 6 sulfotransferase, KS6ST, KSGAL6ST, KSST.

Background: Catalyzes the transfer of sulfate to position 6 of galactose residues of keratan. It has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer. The sulfotransferase activity on sialyl LacNAc structures is much higher than the corresponding desialylated substrate, and only internal galactose residues are sulfated. It also may function in the sulfation of sialyl N-acetyllactosamine oligosaccharide chains attached to glycoproteins. It participates in biosynthesis of selectin ligands. Selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Aggrecan is the major proteoglycan of human articular cartilage. The core protein is substituted by a number of keratan sulfate and chondroitin sulfate glycosaminoglycan chains. Whereas chondroitin sulfate is widely distributed throughout the body, keratan sulfate is primarily expressed in cartilage (joints, trachea, intervertebral discs) and cornea.

Pathways: Glycosaminoglycan Metabolic Process