FGFR1OP anticorps (AA 151-250) (HRP)

N° du produit ABIN1416412

Cet anticorps Lapin Polyclonal détecte spécifiquement FGFR1OP dans WB, ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour FGFR1OP anticorps (AA 151-250) (HRP) (ABIN1416412)

Antigène: FGFR1OP (FGFR1 Oncogene Partner (FGFR1OP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGFR1OP est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-FGFR1OP anticorps (HRP)

Épitope: AA 151-250

Homologie: Human,Mouse,Rat,Dog,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FOP/FGFR1OP

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur FGFR1OP

Antigène: FGFR1OP (FGFR1 Oncogene Partner (FGFR1OP))

Autre désignation: FGFR1OP

Sujet:

Synonyms: FGFR1 oncogene partner, FGFR1OP, Fibroblast growth factor receptor 1 oncogene partner, FOP, FR1OP_HUMAN, OTTHUMP00000017612, OTTHUMP00000017613.

Background: FOP, is a 399 amino acid protein that localizes to the centrosome and contains one LisH domain. Expressed ubiquitously with highest expression in kidney, heart, muscle, colon, liver, testis and pancreas, FOP functions as a homodimer that interacts with EB1 and CEP350 and is essential for anchoring microtubules to centrosomes. Chromosomal aberrations that involve the FOP gene are associated with the pathogenesis of stem cell myeloproliferative disorder (MPD), a condition that is characterized by eosinophilia and myeloid hyperplasia and ultimately leads to acute myeloid leukemia. FOP is expressed as multiple isoforms that are produced by alternative splicing events.

ID gène: 11116

Pathways: M Phase, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome