O3FAR1 anticorps (AA 21-120) (HRP)

N° du produit ABIN1417816

Cet anticorps Lapin Polyclonal détecte spécifiquement O3FAR1 dans WB, ELISA et IHC (fro). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour O3FAR1 anticorps (AA 21-120) (HRP) (ABIN1417816)

Antigène: O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp O3FAR1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-O3FAR1 anticorps (HRP)

Épitope: AA 21-120

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human G protein coupled receptor 120

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur O3FAR1

Antigène: O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))

Autre désignation: GPR120

Sujet:

Synonyms: G protein coupled receptor 120, GPCR GPR120, G protein coupled receptor 129, G protein coupled receptor GT01, G protein coupled receptor PGR 4, G protein coupled receptor PGR4, G-protein coupled receptor 120, G-protein coupled receptor 129, G-protein coupled receptor GT01, G-protein coupled receptor PGR4, GPR 120, GPR 129, GPR120, GPR129, GT01, HGNC:19345, MGC119984, O3FA1_HUMAN, O3FAR1, Omega-3 fatty acid receptor 1, PGR 4, PGR4, GPCR120.

Background: GPR120, a member of the rhodopsin family of G protein-coupled receptors (GPCRs), is a 377 amino acid protein which is expressed in the intestine. GPR120 is a receptor for unsaturated long-chain FFAs (free fatty acids). FFAs act as signaling molecules and are an important energy source. They also employ various physiological responses through their GPCRs. One such response occurs when dietary FFAs stimulate GPR120. This stimulation promotes the secretion of glucagon-like peptide 1 (GLP-1) in vivo and in vitro. GLP-1 belongs to the class of molecules known as the incretins, which are associated with insulin secreted from the pancreas as a result of food intake. GLP-1 also inhibits glucagon and gastric acid secretion and gastric emptying. Consequently, the role of GPR120 in the secretion of GLP-1 is critical in the treatment of diabetes.

ID gène: 338557

UniProt: Q5NUL3

Pathways: Hormone Transport