Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) anticorps (HRP)

N° du produit ABIN1418326

Cet anticorps Lapin Polyclonal détecte spécifiquement Eukaryotic Translation Initiation Factor 3, Subunit M dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) anticorps (HRP) (ABIN1418326)

Antigène: Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PCID1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M)

Autre désignation: PCID1

Sujet:

Synonyms: B5 receptor, Dendritic cell protein, e3m, E3M_HUMAN, Eukaryotic translation initiation factor 3 subunit M, Fetal lung protein B5, FLJ29030, GA17, hfl B5, hFL-B5, PCI domain containing 1 herpesvirus entry mediator, PCI domain-containing protein 1, PCID1.

Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2).

ID gène: 10480

Pathways: Ribonucleoprotein Complex Subunit Organization