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CDK5RAP1 anticorps (HRP)

Cet anticorps Lapin Polyclonal détecte spécifiquement CDK5RAP1 dans WB et IHC (p). Il présente une réactivité envers Humain, Rat et Souris.
N° du produit ABIN1418566

Aperçu rapide pour CDK5RAP1 anticorps (HRP) (ABIN1418566)

Antigène

Voir toutes CDK5RAP1 Anticorps
CDK5RAP1 (CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1))

Reactivité

  • 38
  • 23
  • 21
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
Humain, Rat, Souris

Hôte

  • 38
Lapin

Clonalité

  • 38
Polyclonal

Conjugué

  • 20
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CDK5RAP1 est conjugé à/à la HRP

Application

  • 35
  • 14
  • 13
  • 12
  • 9
  • 5
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  •  Réactivité croisée

    Humain, Souris, Rat

    Purification

    Purified by Protein A.

    Immunogène

    KLH conjugated synthetic peptide derived from human CDK5RAP1

    Isotype

    IgG
  • Indications d'application

    WB 1:300-5000
    IHC-P 1:200-400

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Conseil sur la manipulation

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Date de péremption

    12 months
  • Antigène

    CDK5RAP1 (CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1))

    Autre désignation

    CDK5RAP1

    Sujet

    Synonyms: CDK5 activator binding protein C42 like, CDK5 regulatory subunit associated protein 1, CDK5RAP1.3, CDK5RAP1.4, CGI 05, HSPC167, C20orf34 antibody C42, CDK5 activator binding protein C42, CK5P1_HUMAN.

    Background: Cyclin dependent kinase 5 (Cdk5) is a key regulator of cell cycle progression in neuronal differentiation that physically associates with and is activated by the neuron-specific protein p35. CDK5RAP1 (Cdk5 regulatory subunit-associated protein 1), also known as Cdk5 activator-binding protein C42, is a 601 amino acid protein that specifically inhibits Cdk5 activation by p35 through formation of a dimer that inhibits kinase activity. CDK5RAP1 contains one TRAM domain, which is thought to bind tRNA and deliver the RNA-modifying enzymatic domain to its target. There are 4 named isoforms of CDK5RAP1 that are produced as a result of alternative splicing events and are expressed at high levels in heart and skeletal muscle.

    ID gène

    51654
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