ORAI2 anticorps (HRP)

N° du produit ABIN1421188

Cet anticorps Lapin Polyclonal détecte spécifiquement ORAI2 dans WB et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ORAI2 anticorps (HRP) (ABIN1421188)

Antigène: ORAI2 (ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ORAI2 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-ORAI2 anticorps (HRP)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Orai2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ORAI2

Antigène: ORAI2 (ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2))

Autre désignation: Orai2

Sujet:

Synonyms: C7orf19, CAP binding protein complex interacting protein 2, CBCIP 2, CBCIP2, Chromosome 7 open reading frame 19, FLJ12474, FLJ14733, FLJ44818, H_NH0514P08.8, Orai 2, ORAI calcium release activated calcium modulator 2, Protein orai 2, TMEM 142B, TMEM142B, Transmembrane protein 142B.

Background: Orai2 is a 254 amino acid multi-pass membrane protein that belongs to the orai family of proteins. Localizing to the plasma membrane, Orai2 plays an important role in store-operated calcium (SOC) entry, a process involving Ca2+ influx and replenishment of Ca2+ stores formerly emptied through the action of inositol 1,4,5-trisphosphate production and other Ca2+ mobilizing agents. CRAC channels are responsible for medi-ating calcium influx in T-cells and play an important role in the immune response. Orai2 specifically increases the Ca2+-selective current through coaction with the Ca2+ sensor Stim1.

ID gène: 80228