Transferrin Receptor anticorps (PE-Cy7)

N° du produit ABIN1423934

L’anticorps anti-Transferrin Receptor Polyclonal produit chez le Lapin a été validé pour FACS et WB. Il convient pour la détection de Transferrin Receptor dans des échantillons provenant de Humain, Souris et Rat. }

Aperçu rapide pour Transferrin Receptor anticorps (PE-Cy7) (ABIN1423934)

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Transferrin Receptor est conjugé à/à la PE-Cy7

Application: Flow Cytometry (FACS), Western Blotting (WB)

Détail du produit anti-Transferrin Receptor anticorps (PE-Cy7)

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Pig,Horse,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Transferrin receptor

Isotype: IgG

Information d'application

Indications d'application: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Transferrin Receptor

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Autre désignation: Transferrin receptor

Sujet:

Synonyms: T9, TR, TFR, p90, CD71, TFR1, TRFR, Transferrin receptor protein 1, TFRC

Background: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

Poids moléculaire: 74/85kDa

ID gène: 7037

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis