Vangl1 anticorps (PE-Cy5)

N° du produit ABIN1433384

L’anticorps Lapin Polyclonal anti-Vangl1 a été validé pour WB. Il convient pour détecter Vangl1 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Porc et Poulet.

Aperçu rapide pour Vangl1 anticorps (PE-Cy5) (ABIN1433384)

Antigène: Vangl1 (Vang-Like 1 (Vangl1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Vangl1 est conjugé à/à la PE-Cy5

Application: Western Blotting (WB)

Détail du produit anti-Vangl1 anticorps (PE-Cy5)

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human VANGL1/LPP2

Isotype: IgG

Information d'application

Indications d'application: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Vangl1

Antigène: Vangl1 (Vang-Like 1 (Vangl1))

Autre désignation: VANGL1/LPP2

Sujet:

Synonyms: Loop tail protein 2 homolog, Loop-tail protein 2 homolog, LPP2, MGC5338, STB2, STBM2, Strabismus 2, Van Gogh like protein 1, Van Gogh-like protein 1, vang like 1 van gogh, Drosophila, Vang like protein 1, Vang-like protein 1, VANG1_HUMAN, VANGL 1, Vangl1.

Background: The Vang family of proteins are integral membrane proteins that are homologues of the Drosophila tissue polarity gene strabismus. The gene encoding for Van Gogh-like protein 1 (Vangl1), also designated Strabismus 2 (STB2), localizes to human chromosome 1p11-p13.1. Van Gogh-like protein 2 (Vangl2), also designated Strabismus 1 (STB1), localizes to chromosome 1q22-q23. Vangl1 is expressed primarily in testis and ovary, but is also expressed in gastric and pancreatic cancer. Vangl proteins play a key developmental role in establishing planar cell polarity (PCP) and in regulating convergent extension (CE) movements during embryogenesis. Vangl1 and Vangl2 are both downregulated in several cancer cell lines and primary tumors.

Poids moléculaire: 60 kDa

ID gène: 8612

Pathways: Signalisation WNT