ZNRF3 anticorps (PE)

N° du produit ABIN1434637

Cet anticorps Lapin Polyclonal détecte spécifiquement ZNRF3 dans IF (p). Il présente une réactivité envers Humain, Souris, Rat, Poulet, Boeuf (Vache), Chien et Porc.

Aperçu rapide pour ZNRF3 anticorps (PE) (ABIN1434637)

Antigène: ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))

Reactivité: Humain, Souris, Rat, Poulet, Boeuf (Vache), Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNRF3 est conjugé à/à la PE

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-ZNRF3 anticorps (PE)

Réactivité croisée: Rat (Rattus), Poulet, Chien, Porc, Boeuf (Vache)

Purification: purified by Protein A

Immunogène: KLH conjugated synthetic peptide derived from human ZNRF3

Isotype: IgG

Information d'application

Commentaires:

Excitation / Emission wavelength: 496nm / 578nm

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4 °C for 12 months

Date de péremption: 12 months

Détails sur ZNRF3

Antigène: ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))

Autre désignation: ZNRF3

Sujet: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). ZNRF3 (Zinc/RING finger protein 3), also known as RNF203 (RING finger protein 203), is a 936 amino acid single pass transmembrane protein that contains one RING-type zinc finger. Related zinc/RING finger proteins, such as ZNRF1 and ZNRF2, are E3 ubiquitin-protein ligases that are thought to be involved in the establishment and maintenance of neuronal transmission and plasticity, therefore it is likely that ZNRF3 may function in a similar manner.

ID gène: 84133

HGNC: 0

Pathways: Signalisation WNT