RAB27A anticorps (C-Term)

N° du produit ABIN1440000

Cet anticorps anti-RAB27A est un anticorps Chèvre Polyclonal détectant RAB27A dans WB, IF, IHC (p) et IHC (fro). Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chévre, Cheval, Mouton, Chien, Cobaye, Lapin, Singe, Poulet, Porc, Cat, Âne, Hamster et Avian. Ce Primary Antibody a été cité dans 3+ publications.

Aperçu rapide pour RAB27A anticorps (C-Term) (ABIN1440000)

Antigène: RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chévre, Cheval, Mouton, Chien, Cobaye, Lapin, Singe, Poulet, Porc, Cat, Âne, Hamster, Avian

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB27A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-RAB27A anticorps

Épitope: C-Term

Specificité: Detects Rab27a by Western blot in the following human, rat and mouse whole cell lysates and transfected cells with GFP-Rab27a. This antibody also recognizes Rab27b protein.

Attributs du produit: RAB27A, member RAS oncogene family

Purification: epitope affinity purified

Immunogène: Purified recombinant peptide derived from within residues 120 aa to the C-terminus of mouse Rab27a produced in E. coli.

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Polyclonal antibody supplied as a 200 µL (1 mg/mL) aliquot in PBS, 20 % glycerol and 0.05 % sodium azide

Conseil sur la manipulation: The antibody solution should be gently mixed before use.

Stock: 4 °C,-20 °C

Stockage commentaire: For continuous use, store at 2-8 deg,C for one-two days. For extended storage, store in -20 deg,C freezer. Working dilution samples should be discarded if not used within 12 hours.

Références pour anticorps anti-RAB27A (ABIN1440000)

Alzahofi, Welz, Robinson, Page, Briggs, Stainthorp, Reekes, Elbe, Straub, Kallemeijn, Tate, Goff, Sviderskaya, Cantero, Montoliu, Nedelec, Miles, Bailly, Kerkhoff, Hume: "Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins." dans: Nature communications, Vol. 11, Issue 1, pp. 3495, (2020) (PubMed).

Pelkonen, Reinisalo, Morin-Picardat, Kidron, Urtti: "Isolation of Intact and Functional Melanosomes from the Retinal Pigment Epithelium." dans: PLoS ONE, Vol. 11, Issue 8, pp. e0160352, (2017) (PubMed).

Reichhart, Markowski, Ishiyama, Wagner, Crespo-Garcia, Schorb, Ramalho, Milenkovic, Föckler, Seabra, Strauß: "Rab27a GTPase modulates L-type Ca2+ channel function via interaction with the II-III linker of CaV1.3 subunit." dans: Cellular signalling, Vol. 27, Issue 11, pp. 2231-40, (2016) (PubMed).

Détails sur RAB27A

Antigène: RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

Autre désignation: Rab27a

Sujet: Rab27a belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and involved in lysosome-related vesicle transport and small GTPase mediated signal transduction.
Synonyms: GS2, GTP-binding protein Ram, rab-27, ras-related protein Rab-27A, RAB27, RAM.
Ensembl identifier: ENSG00000069974

Pathways: Peptide Hormone Metabolism