Calnexin anticorps (C-Term)

N° du produit ABIN1440008

Cet anticorps Chèvre Polyclonal détecte spécifiquement Calnexin dans WB, IF, IHC (p) et IHC (fro). Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Singe, Lapin, Cobaye, Porc, Hamster, Mouton, Poulet, Avian, Cheval, Chévre, Cat et Âne. Il a été cité dans 3+ publications.

Aperçu rapide pour Calnexin anticorps (C-Term) (ABIN1440008)

Antigène: Calnexin (CANX)

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Singe, Lapin, Cobaye, Porc, Hamster, Mouton, Poulet, Avian, Cheval, Chévre, Cat, Âne

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Calnexin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Calnexin anticorps

Épitope: C-Term

Fonction: Anti-CANX

Séquence: KSDAEEDGGT VSQEEEDRKP KAEEDEILNR SPRNRKPRRE

Specificité: Detects a band of 90 kDa by Western blot in the following human (293A, primary fibroblasts, HaCat, HeLa, HMEC-1, Jurkat, MNT1, U-118, rat (TR-iBRB), mouse (3T3, AtT-20, Hepa, Raw264.7), monkey (COS-7) and canine (D17) whole cell lysates.

Attributs du produit: Calnexin

Purification: Epitope affinity purified

Immunogène: Purified recombinant peptide within residues 550 aa to the C-terminus of human CANX produced in E. coli.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:5,000, IF:1:50-1:500, IHC-P:1:200-1:1,000, IHC-F:1:200-1:1,000

Restrictions: For Research Use only

Stockage

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: The antibody solution should be gently mixed before use.

Stock: 4 °C,-20 °C

Stockage commentaire: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Références pour anticorps anti-Calnexin (ABIN1440008)

Pelkonen, Sato, Reinisalo, Kidron, Tachikawa, Watanabe, Uchida, Urtti, Terasaki: "LC-MS/MS Based Quantitation of ABC and SLC Transporter Proteins in Plasma Membranes of Cultured Primary Human Retinal Pigment Epithelium Cells and Immortalized ARPE19 Cell Line." dans: Molecular pharmaceutics, Vol. 14, Issue 3, pp. 605-613, (2017) (PubMed).

Martins-Marques, Pinho, Zuzarte, Oliveira, Pereira, Sluijter, Gomes, Girao: "Presence of Cx43 in extracellular vesicles reduces the cardiotoxicity of the anti-tumour therapeutic approach with doxorubicin." dans: Journal of extracellular vesicles, Vol. 5, pp. 32538, (2016) (PubMed).

Ribot, Ribeiro, Correia, Sousa, Silva-Santos: "Human ?? thymocytes are functionally immature and differentiate into cytotoxic type 1 effector T cells upon IL-2/IL-15 signaling." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 5, pp. 2237-43, (2014) (PubMed).

Détails sur Calnexin

Antigène: Calnexin (CANX)

Autre désignation: CANX

Sujet:

Goat polyclonal to CANX (Calnexin) - endoplasmic reticulum (ER) membrane marker. CANX is a member of the calnexin family of molecular chaperones. This protein is a calcium-binding, ER-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.

Calnexin, CALX, CNX, FLJ26570, histocompatibility complex class I antigen binding protein p88, IP90, major histocompatibility complex class I antigen-binding protein p88, MS952, P90 antibody.

Pathways: Signalisation MAPK, Thyroid Hormone Synthesis