RNF2 anticorps

N° du produit ABIN1449179

Détail du produit anti-RNF2 anticorps

Antigène: RNF2 (Ring Finger Protein 2 (RNF2))

Reactivité: Humain, Souris, Hamster

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RNF2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Specificité: This antibody reacts with Ring1B.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Hamster

Purification: Protein-A Sepharose

Immunogène: GST fusion mouse full-length Ring1B protein

Clone: 03-03-14

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur RNF2

Antigène: RNF2 (Ring Finger Protein 2 (RNF2))

Autre désignation: RNF2 (RNF2 Produits)

Sujet: Polycomb-group (PcG) proteins form multimeric complexes that maintain the state of transcriptional repression of several regulatory genes during development. Ring1B/Rnf2 forms part of a protein complex containing other PcG proteins, such as Mel18, Bmi1, MBLR, MPc3, and the spliceosome protein Sap155, and these complexes associate with chromatin to regulate transcription. Ring1B may also play a role in the regulation of Hox gene expression by PcG complexes. Deletion of Ring1B activity results in gastrulation arrest and cell cycle inhibition.Synonyms: BAP-1, BAP1, DING, E3 ubiquitin-protein ligase RING2, HIP2-interacting protein 3, HIPI3, Protein DinG, RING finger protein 2, RING1B

ID gène: 6045

NCBI Accession: NP_009143

UniProt: Q99496